Tumour Angiogenesis (Hardback)
  • Tumour Angiogenesis (Hardback)
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Tumour Angiogenesis (Hardback)

(editor), (editor), (editor)
£167.50
Hardback 396 Pages / Published: 03/07/1997
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Tumour Angiogenesis is the first comprehensive book to cover all areas of this rapidly expanding research area. Each chapter is written by world experts in the field and topics covered include in vivo models, mechanisms, inhibition, and the role of macrophages, cytokines, proteases, extracellular matrix components, nitric oxide, prostanoids and oncogenes/tumour suppressor genes in angiogenesis. Other chapters examine the role of specific growth factors in angiogenesis - these include vascular endothelial growth factor, the basic fibroblast growth factor family, transforming growth factor-beta, tumour necrosis factor-alpha, platelet-derived endothelial cell growth factor/thymidine phosphorylase and pleiotrophin and related molecules. Clinical issues are addressed in chapters that deal with the prognostic and predictive value of tumour microvessel density and the therapeutic significance of microregional blood flow. The two final chapters examine the feasibility of targeting tumour vasculature using either antibodies or gene therapy.

Publisher: Oxford University Press
ISBN: 9780198549376
Number of pages: 396
Weight: 1163 g
Dimensions: 255 x 198 x 28 mm


MEDIA REVIEWS
'...a timely book about an area that is rapidly gaining in popularity...this contribution will be most useful for the researchers in the field, in particular for scientists new to angiogenesis who will benefit from this extensive and thorough introduction. The book will also function well as a dictionary for people working in related areas...this is an extensive, well written and comprehensive book.' * Trends in Cell Biology (Vol.8) October 1998. *
'This is an interesting book...' * Cellular & Molecular Biology, June vol.44/No.4, 1998. *

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