The Development of the Perineum in the Human: A Comprehensive Histological Study with a Special Reference to the Role of the Stromal Components - Advances in Anatomy, Embryology and Cell Biology 177 (Paperback)
  • The Development of the Perineum in the Human: A Comprehensive Histological Study with a Special Reference to the Role of the Stromal Components - Advances in Anatomy, Embryology and Cell Biology 177 (Paperback)
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The Development of the Perineum in the Human: A Comprehensive Histological Study with a Special Reference to the Role of the Stromal Components - Advances in Anatomy, Embryology and Cell Biology 177 (Paperback)

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Paperback 136 Pages / Published: 06/10/2004
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References...126 Subject Index...133 1 Introduction The developmental steps which lead to the formation of the human perineum seem firmly established (Arey 1965; Hamilton and Mossman1972; Moore and Persaud 1998; Wartenberg 1993; Sadler 1995; Larsen 1997). They form the base for the evaluation of the pathogenesis of a great variety of complicated and often serious malformations which occur in this region. This concept has, however, been challenged by the results of an investigation into the n- mal and abnormal development of the anorectum in pig (van der Putte and Neeteson 1983, 1984; van der Putte 1986). Observations revealed that at least in pig, a major element in current ideas about the early development of the perineum, namely the process by which the original simple cloaca is sub- vided into a urogenital and anal part is incorrect, while additional obser- tions strongly suggested that the same may be true for ideas about female and male sexual transformation. A preliminary investigation in human - bryos gave similar indications (van der Putte 1986). The data supported e- lier critical findings (Politzer 1931, 1932; Wijnen 1964; Ludwig 1965) which have apparently been ignored, possibly because they seemed to hinder the understanding of the pathogenesis of congenital malformations such as - perforate anus and hypospadias.

Publisher: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
ISBN: 9783540210399
Number of pages: 136
Weight: 237 g
Dimensions: 235 x 155 x 8 mm
Edition: 2005 ed.

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