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The Breakthrough: immunotherapy and the race to cure cancer (Paperback)
  • The Breakthrough: immunotherapy and the race to cure cancer (Paperback)
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The Breakthrough: immunotherapy and the race to cure cancer (Paperback)

(author)
£16.99
Paperback 320 Pages / Published: 15/11/2018
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Detailing the cutting-edge work that was awarded the 2018 Nobel Prize for Medicine.

New York Times bestselling author Charles Graeber tells the astonishing story of the group of scientists working on a code that can enable the human immune system to fight - and perhaps even cure - cancer.

For decades, scientists have puzzled over one of medicine's greatest mysteries: why doesn't our immune system fight cancer the way it does other diseases? The answer is a series of tricks that cancer has developed to turn off normal immune responses - tricks that scientists have only recently discovered, and now are learning to defeat. We are in the midst of a revolution in our understanding of cancer and how to beat it.

Groundbreaking, riveting, and expertly told, The Breakthrough is the story of the game-changing scientific discoveries that unleash our natural ability to recognise and defeat cancer, as told through the experiences of the patients, physicians, and immunotherapy researchers who are on the front lines. This is the incredible true story of the race to find a cure, and the definitive account of a historic moment in medical science.

Publisher: Scribe Publications
ISBN: 9781911344865
Number of pages: 320
Dimensions: 234 x 153 x 23 mm


MEDIA REVIEWS

`Only Graeber, one of America's greatest non-fiction writers, could take a subject so complex, dense and sprawling and turn it into a rollicking high-tension medical thriller. Masterful.'

-- Douglas Rogers, award-winning journalist and author of The Last Resort

`A gripping chronicle of the 100-year overnight success of immunotherapy. For myself and millions of other cancer survivors, The Breakthrough is a book of immense and essential hope.'

-- Michael Fitzgerald, co-founder and CEO of Submittable and author of Radiant Days

`There is no villain more ruthless than cancer, which has robbed us all of loved ones who had to endure untold suffering before they succumbed. But after decades of frustration and toil, scientists finally understand how to vanquish the disease by activating the human body's natural defences. The intimate stories behind this triumph lie at the heart of Charles Graeber's The Breakthrough, an expertly crafted and exhilarating account of life-saving ingenuity at its most dazzling. You will never encounter another book so incisive about the art of medical sleuthing, or so poetic about our innate drive to hold on to all that's beautiful in this world for as long as we can.'

-- Brendan I. Koerner, Wired contributing editor and author of The Skies Belong to Us

`Lucid and informed ... Graeber gives readers a basis for both understanding the challenges involved and for cautious optimism that a cure can be found.'

* Publishers Weekly *

`Graeber concisely reviews the science of cancer ... The risks of tinkering with an intricate immune system are obviously high, even perilous. But the potential reward is a cure. Exciting reading.'

* Booklist *

`Imagine a vaccine that could cure cancer. As this book reports, that possibility may not be far off ... [T]he book offers hope for more effective treatments in the near future. A readable survey of the emerging field of immunotherapy in cancer treatment.'

* Kirkus *

Praise for The Good Nurse:

`A stunning book ... that should and does bring to mind In Cold Blood ... the story appeals to prurient interests, as does any graphic tale of true crime. But The Good Nurse succeeds in being about much more than Mr. Cullen's murderous kinks. The causes of his pathology are not interesting. But the eagerness of ambitious hospital administrators to cover up his misdeeds is revelatory. And the police investigation that brought him down is a thriller in every sense of that word.'

* New York Times *

Praise for The Good Nurse:

`The most terrifying book published this year. It is also one of the most thoughtful ... From a long series of conversations with Cullen, the detectives who solved the case and Amy, a nurse who once was Cullen's best friend and eventually got him to confess, among many other sources, Graeber has crafted a book that is a revelation. The Good Nurse is gripping, sad, suspenseful, rhythmic and beautifully documented (the endnotes to this book are impressive).'

* Kirkus Reviews *

Praise for The Good Nurse:

`Graeber doesn't pull punches ... A deeply unsettling addition to the true crime genre.'

* Publishers Weekly *

Praise for The Good Nurse:

`Engrossing ... hard-to-put-down ... On one level, The Good Nurse is an absorbing story of a serial killer operating within the walls of what most view as a trusted institution. On another, it's an intriguing detective story. And on another it's an indictment of the hospital industry.'

* The New Jersey Star-Ledger *

Praise for The Good Nurse:

`A remarkable new book ... gripping and brilliantly written.'

* Healthcare Risk Management *

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