• Sign In / Register
  • Help
  • Basket0
The Blood-Brain Barrier, Amino Acids and Peptides (Paperback)
  • The Blood-Brain Barrier, Amino Acids and Peptides (Paperback)
zoom

The Blood-Brain Barrier, Amino Acids and Peptides (Paperback)

(author), (author)
£119.99
Paperback 202 Pages / Published: 01/10/2011
  • We can order this

Usually despatched within 3 weeks

  • This item has been added to your basket
Definition of the barrier The interstitial fluid (rSF) of the brain is separated from the blood by the blood-brain barrier (BBB). This barrier must not be thought of as a single entity or as an absolute restriction to all molecules, but as a multiple structure located at several sites within the brain. The first of these interfaces is located at the endothelium of the brain capillaries. Secondly there is a potential site for interchange on the outer linings of the brain between the dura and the arachnoid membranes. Thirdly, there are the choroid plexuses and the cerebrospinal fluid (CSF) which is in contact with the very permeable internal ependymal lining of the brain (Figure 1. 1). Finally there are areas of the brain which lack a blood-brain barrier. These areas constitute the circumventricu- lar organs and have leaky capillaries with a barrier at the ependyma which limits the spread of molecules from those regions (Figure 1. 2). Each of these BBB sites has its own characteristic permeability and transport functions. We will now consider the properties of each of these barrier sites between the blood and the brain. THE CEREBRAL CAPILLARY ENDOTHELIUM Morphology This interface has both the largest surface area and the shortest path length between the blood and the brain rSF. The cerebral capillaries, which at first sight seem little different from the rest of the systemic circulation, are in fact unique to the brain.

Publisher: Springer
ISBN: 9789401075008
Number of pages: 202
Weight: 332 g
Dimensions: 235 x 155 x 11 mm
Edition: Softcover reprint of the original 1st ed. 199

You may also be interested in...

Picasso's Brain
Added to basket
£14.99
Paperback
The Handbook of Clinical Neuropsychology
Added to basket
The Autistic Brain
Added to basket
Emotion: A Very Short Introduction
Added to basket
Brain Rules (Updated and Expanded)
Added to basket
Incognito
Added to basket
£9.99
Paperback
The Runaway Species
Added to basket
Educational Neuroscience
Added to basket
The Tale of the Duelling Neurosurgeons
Added to basket
Delusions of Gender
Added to basket
Mind Change
Added to basket
£9.99
Paperback
30-Second Brain
Added to basket
This Idea Must Die
Added to basket
The Future of the Mind
Added to basket
The Private Life of the Brain
Added to basket
The Origins of Virtue
Added to basket

Reviews

Please sign in to write a review

Your review has been submitted successfully.