TGF-ss Signaling: Methods and Protocols - Methods in Molecular Biology 1344 (Hardback)
  • TGF-ss Signaling: Methods and Protocols - Methods in Molecular Biology 1344 (Hardback)
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TGF-ss Signaling: Methods and Protocols - Methods in Molecular Biology 1344 (Hardback)

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£109.99
Hardback 394 Pages / Published: 05/11/2015
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This volume details up-to-date information and attempts to take the reader into the exciting realm of TGF-ss from the basic principles to the practical applications. Chapters provide basic introduction of TGF-ss signaling from the cell surface to the nucleus, methods and techniques for the investigation of TGF-ss signaling mechanism including receptors, Smads, intracellular kinases, microRNA, epigenetic regulation, post-translational regulations, non-Smad pathway; the physiological implications including those in cell cycle arrest, epithelial-mesenchymal transition, endothelial cells, adipogenesis, Th differentiation, stem cell, bone remodeling, ovary, zebrofish development, and frog animal capping; and the methodologies including metastasis imaging, 3D morphogenesis, membrane receptor quantification, conditional knockout, bone remodeling, kinase and phosphatase assays, BiFC interaction assays, and genome-wide siRNA screen. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls.

Authoritative and practical, TGF-Beta Signaling: Methods and Protocols aims to ensure successful results in the further study of this vital field.

Publisher: Humana Press Inc.
ISBN: 9781493929658
Number of pages: 394
Weight: 9992 g
Dimensions: 254 x 178 x 28 mm
Edition: 1st ed. 2016

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