Temperature and Toxicology: An Integrative, Comparative, and Environmental Approach (Hardback)Christopher J. Gordon (author)
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The book begins by explaining the importance of temperature in toxicological studies, and how all biological processes are dependent on temperature. It then reviews the basics of temperature regulation in homeotherms and poikilotherms, and addresses whole-animal and in vitro studies related to the effects of temperature on toxicity. The text examines thermoregulatory response to toxic insult, and how responses affect recovery and potential survival. It describes hypothermic response in rodents to febrile and hyperthermic reactions in humans, and discusses the relevance of heat and cold stress on human exposures to airborne pollutants and other toxicants.
This volume provides an extensive comparison of physiological responses of invertebrates, fish, amphibians, and mammals, and focuses on the impact of endocrine disruption. It then considers how toxicants and thermal stress cause the expression of stress proteins, followed by a study of the impact of genetic variability. The book concludes with an examination of thermoregulatory response to natural toxins and venoms.
Publisher: Taylor & Francis Inc
Number of pages: 338
Weight: 612 g
Dimensions: 235 x 156 x 24 mm
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