Stress-Induced Mutagenesis (Paperback)
  • Stress-Induced Mutagenesis (Paperback)
zoom

Stress-Induced Mutagenesis (Paperback)

(editor)
£129.99
Paperback 275 Pages / Published: 03/04/2015
  • We can order this

Usually dispatched within 3 weeks

  • This item has been added to your basket

The discovery of stress-induced mutagenesis has changed ideas about mutation and evolution, and revealed mutagenic programs that differ from standard spontaneous mutagenesis in rapidly proliferating cells. The stress-induced mutations occur during growth-limiting stress, and can include adaptive mutations that allow growth in the otherwise growth-limiting environment. The stress responses increase mutagenesis specifically when cells are maladapted to their environments, i.e. are stressed, potentially accelerating evolution then. The mutation mechanism also includes temporary suspension of post-synthesis mismatch repair, resembling mutagenesis characteristic of some cancers. Stress-induced mutation mechanisms may provide important models for genome instability underlying some cancers and genetic diseases, resistance to chemotherapeutic and antibiotic drugs, pathogenicity of microbes, and many other important evolutionary processes.

This book covers pathways of stress-induced mutagenesis in all systems. The principle focus is mammalian systems, but much of what is known of these pathways comes from non-mammalian systems.

Publisher: Springer-Verlag New York Inc.
ISBN: 9781489994189
Number of pages: 275
Weight: 4453 g
Dimensions: 235 x 155 x 15 mm
Edition: 2013 ed.

You may also be interested in...

The Seven Daughters Of Eve
Added to basket
The Cosmic Serpent
Added to basket
£8.99
Paperback
Mutants
Added to basket
£12.99
Paperback
The Violinist's Thumb
Added to basket
£9.99
Paperback
Introducing Genetics
Added to basket
Nature via Nurture
Added to basket
£10.99
Paperback
Identically Different
Added to basket
The Epigenetics Revolution
Added to basket
The Britannica Guide to Genetics
Added to basket
Endless Forms Most Beautiful
Added to basket
Genes: A Very Short Introduction
Added to basket
River Out of Eden
Added to basket
Genograms
Added to basket
£23.00
Paperback

Reviews

Please sign in to write a review

Your review has been submitted successfully.