While most stem cell books focus on basic aspects and/or cell therapy, this book emphasizes the relevance of stem cells obtained from patients, the so-called "patients in a petri dish" as tools to investigate human genetic diseases for which there are no available effective treatment. Chapters embrace several examples of the use of iPS cell technology, a recent Nobel Prize-winning scientific breakthrough, to obtain patient-specific pluripotent cells from which many types of specialized cells involved in a particular disease can be generated, including psychiatric and neurodegenerative disorders, muscular dystrophies, laminopathies, among others. The text is a current and timely resource for postgraduate students, scientists and clinicians, interested in applications of this rapidly developing field of research in disease modeling, drug development, and emerging issues that it brings to regenerative medicine.
Publisher: Springer International Publishing AG
Number of pages: 147
Weight: 2817 g
Dimensions: 235 x 155 mm
Edition: Softcover reprint of the original 1st ed. 201
"The target audience of this book are students, researchers and clinicians interested in the recent developments in the field. The book is well written and, thanks to the good introductory section in each of the chapters, even non-experts in the field will be able to follow. The figures in the book are well-designed ... . The book gives a good overview about the current state of research in these fields and can therefore be recommended for interested readers." (Christian Schnell, Human Genetics, Vol. 135, 2016)