Stem Cell Biology in Neoplasms of the Central Nervous System - Advances in Experimental Medicine and Biology 853 (Hardback)Moneeb Ehtesham (editor)
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This volume presents the most current reviews on how cancer stem cells (CSCs) hypothesis dictates that the continued proliferation of a tumor is dependent on a sub-population of self-renewing and asymmetrically dividing neoplastic stem cells that supply a largely differentiated tumor. This volume provides a comprehensive overview of the characteristics of CSCs, their role in central nervous system (CNS) tumors, and the recent CSC-specific treatment modalities being used.
The emerging focus on CSCs in brain tumors represents a paradigm shift in our understanding of the pathogenesis of these neoplasms. Importantly, the realization that a distinct sub-population of cells contributes disproportionately to the growth and sustenance of central nervous system tumors has important implications for the treatment of such tumors. To treat CNS tumors, there is now a growing need to treat CSCs to achieve adequate tumor control.
Publisher: Springer International Publishing AG
Number of pages: 190
Weight: 545 g
Dimensions: 235 x 155 x 13 mm
Edition: 2015 ed.
"This is an excellent textbook regarding the molecular and cell biology with respect to brain and spine neoplasms. This is a good book to look at and study if you are interested how cancer comes about. ... Research neurologists and neurosurgeons will find the book useful for their animal research. ... Graduate students, research fellows, and neuropathologists will be interested in the work presented here." (Joseph J. Grenier, Amazon.com, August, 2015)
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