Smart Internal Stimulus-Responsive Nanocarriers for Drug and Gene Delivery (Paperback)
  • Smart Internal Stimulus-Responsive Nanocarriers for Drug and Gene Delivery (Paperback)
zoom

Smart Internal Stimulus-Responsive Nanocarriers for Drug and Gene Delivery (Paperback)

(author), (author), (author), (author)
£45.50
Paperback 115 Pages / Published: 30/12/2015
  • We can order this

Usually dispatched within 3 weeks

  • This item has been added to your basket
The concept of smart drug delivery vehicles involves designing and preparing a nanostructure (or microstructure) that can be loaded with a cargo. This can be a therapeutic drug, a contrast agent for imaging, or a nucleic acid for gene therapy. The nanocarrier serves to protect the cargo from degradation by enzymes in the body, to enhance the solubility of insoluble drugs, to extend the circulation half-life, and to enhance its penetration and accumulation at the target site. Importantly, smart nanocarriers can be designed to be responsive to a specific stimulus, so that the cargo is only released or activated when desired. In this volume we cover smart nanocarriers that respond to internal stimuli that are intrinsic to the target site. These stimuli are specific to the cell type, tissue or organ type, or to the disease state (cancer, infection, inflammation etc). pH-responsive nanostructures can be used for cargo release in acidic endosomal compartments, in the lower pH of tumors, and for specific oral delivery either to the stomach or intestine. Nanocarriers can be designed to be substrates of a wide-range of enzymes that are over-expressed at disease sites. Oxidation and reduction reactions can be taken advantage of in smart nanocarriers by judicious molecular design. Likewise, nanocarriers can be designed to respond to a range of specific biomolecules that may occur at the target site. In this volume we also cover dual and multi-responsive systems that combine stimuli that could be either internal or external.

Publisher: Morgan & Claypool Publishers
ISBN: 9781681742564
Number of pages: 115
Weight: 214 g
Dimensions: 254 x 175 x 6 mm

You may also be interested in...

Lancaster Target
Added to basket
£7.99
Paperback
The Boy Who Harnessed the Wind
Added to basket
BTEC National Engineering, 3rd ed
Added to basket
Bad Ideas?
Added to basket
£9.99
Paperback
Who Owns The Future?
Added to basket
Thus Spoke Galileo
Added to basket
£30.49
Paperback
Making It, 2nd edition
Added to basket
Mathematics for Physics
Added to basket
Leonardo da Vinci
Added to basket
Engineering
Added to basket
£9.99
Paperback
Guide to Urban Engineering
Added to basket
Numerical Methods for Engineers
Added to basket
Structures
Added to basket
£14.99
Paperback

Reviews

Please sign in to write a review

Your review has been submitted successfully.