Your Waterstones card is changing, introducing...
TELL ME MORE
Signaling Pathways for Translation: Insulin and Nutrients - Progress in Molecular and Subcellular Biology 26 (Hardback)
  • Signaling Pathways for Translation: Insulin and Nutrients - Progress in Molecular and Subcellular Biology 26 (Hardback)
zoom

Signaling Pathways for Translation: Insulin and Nutrients - Progress in Molecular and Subcellular Biology 26 (Hardback)

(editor)
£129.99
Hardback 186 Pages / Published: 17/07/2001
  • We can order this

Usually despatched within 3 weeks

  • This item has been added to your basket
The articles in the present volume are by major contributors to our under- standing of signaling pathways affecting protein synthesis. They focus pri- marily on two extracellular anabolic signals, although others are included as well. Insulin is one of the best-studied extracellular regulators of protein syn- thesis. Several of the known pathways for regulation of protein synthesis were elucidated using insulin-dependent systems. Regulation of protein synthesis by amino acids, by contrast, is an emerging field that has recently received a great deal of attention. The dual role of amino acids as substrates for protein syn- thesis and regulators of the overall process has only recently been recognized. Since amino acids serve as precursors for proteins, one might expect that with- holding an essential amino acid would inhibit the elongation phase. Surpris- ingly, research has shown that it is the initiation phase of protein synthesis that is restricted during amino acid starvation. Understanding the mechanisms by which the biosynthesis of proteins is reg- ulated is important for several reasons. Protein synthesis consumes a major portion of the cellular ATP that is generated. Therefore, small changes in protein synthesis can have great consequences for cellular energy metabolism. Translation is also a major site for control of gene expression, since messenger RNAs differ widely in translational efficiency, and changes to the protein syn- thesis machinery can differentially affect recruitment of individual mRNAs.

Publisher: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
ISBN: 9783540417095
Number of pages: 186
Weight: 467 g
Dimensions: 235 x 155 x 12 mm
Edition: 2001 ed.

You may also be interested in...

A Dictionary of Biology
Added to basket
Mathematics for Biological Scientists
Added to basket
The Shaping of Cambridge Botany
Added to basket
Biophysics
Added to basket
£69.99
Hardback
Thrive in Cell Biology
Added to basket
The Neuron
Added to basket
£68.00
Hardback
The Cell: A Very Short Introduction
Added to basket
On Growth and Form
Added to basket
In Search of Cell History
Added to basket
Secret Chambers
Added to basket
£10.99
Paperback
Physical Biology of the Cell
Added to basket
Molecular & Cell Biology for Dummies
Added to basket
Bacterial Disease Mechanisms
Added to basket
How We Live and Why We Die
Added to basket

Reviews

Please sign in to write a review

Your review has been submitted successfully.