• Sign In / Register
  • Help
  • Basket0
Regulation of Immune Gene Expression - Experimental Biology and Medicine 13 (Paperback)
  • Regulation of Immune Gene Expression - Experimental Biology and Medicine 13 (Paperback)
zoom

Regulation of Immune Gene Expression - Experimental Biology and Medicine 13 (Paperback)

(author), (author)
£127.50
Paperback 360 Pages / Published: 04/02/2012
  • We can order this

Usually despatched within 3 weeks

  • This item has been added to your basket
This book encompasses the proceedings of a conference held at Trinity College, Oxford on September 21-25, 1985 organized by a committee comprised of Drs. M. Crumpton, M. Feldmann, A. McMichael, and E. Simpson, and advised by many friends and colleagues. The immune response gene workshops that took place were based on the need to understand why certain experimental animal strains were high responders and others were low responders. It was assumed that identification of the immune response (Ir) genes and definition of their products would explain high and low responder status. Research in the ensuing years has identified the Ir gene products involved in antibody responses as the la antigens, or MHC Class II antigens. These proteins are now well defined as members of the immunoglobulin gene superfamily, and their domain structure is known. Epitopes have been defined by multiple mono- clonal antibodies and regions of hypervariability identified. Their genes have been identified and cloned. The basic observation of high and low responsive- ness to antigen is still not understood in mechanistic terms, however, at either the cellular or molecular level. This is because the rate of progress in immune regulation has been far slower than in the molecular biology of the MHC Class II antigens. This is not surprising, since immune regulation is a very complex field at the crossroads of many disciplines.

Publisher: Humana Press Inc.
ISBN: 9781461293996
Number of pages: 360
Weight: 575 g
Dimensions: 235 x 155 x 20 mm
Edition: Softcover reprint of the original 1st ed. 198

You may also be interested in...

The Salicylate Handbook
Added to basket
Boosting Your Immunity for Dummies
Added to basket
Lippincott Illustrated Reviews: Immunology
Added to basket
Kuby Immunology
Added to basket
£62.99
Paperback
Intolerant Bodies
Added to basket
The Lock and Key of Medicine
Added to basket
Histamine Intolerance
Added to basket
Oxford Handbook of Clinical Immunology and Allergy
Added to basket
BIOS Instant Notes in Immunology
Added to basket
The Infectious Microbe
Added to basket
Infection & Immunity
Added to basket
Immunology
Added to basket
£46.99
Paperback
Mind, Immunity and Health
Added to basket

Reviews

Please sign in to write a review

Your review has been submitted successfully.