Visit our Christmas Gift Finder
Proton Pump Inhibitors - Milestones in Drug Therapy (Paperback)
  • Proton Pump Inhibitors - Milestones in Drug Therapy (Paperback)
zoom

Proton Pump Inhibitors - Milestones in Drug Therapy (Paperback)

(editor)
£119.99
Paperback 251 Pages / Published: 03/10/2013
  • We can order this

Usually dispatched within 3 weeks

  • This item has been added to your basket
Inhibition of the proton pump in the parietal cells has been established as the main therapeutic principle in the treatment of acid-related diseases, such as peptic ulcer and gastro-oesophageal reflux. The proton pump inhi- bitors are tailored for their purpose. They accumulate in the target cell, are activated by acid and bind strongly to the specific target - the proton pump. The clinical superiority of the proton pump inhibitors is due not only to their high efficacy but also to the long duration of the acid inhibition in comparison with other antisecretory drugs. At present when drug discovery mostly relies on identification and characterization of potential targets by genome research, molecular biology, combinatorial chemistry and automated screening, it seems worthwhile to present the development of the tITst proton pump inhibitor - omeprazol- starting from a chemical structure with an observed antisecretory effect but also severe toxic effects that had to be eliminated. As always, basic and applied research operate luind in hand to optimize the delicate balance be- tween efficacy and safety of a new drug. This goal often involves time and many different specialists.

Publisher: Springer Basel
ISBN: 9783034897778
Number of pages: 251
Weight: 467 g
Dimensions: 244 x 170 x 14 mm
Edition: Softcover reprint of the original 1st ed. 199

You may also be interested in...

The Citadel
Added to basket
£16.99
Paperback
Concise Colour Medical Dictionary
Added to basket
£14.99
Part-work (fascículo)
Catch Up Maths & Stats, second edition
Added to basket
Black's Student Medical Dictionary
Added to basket
Oxford Handbook of General Practice
Added to basket
£34.99
Part-work (fascículo)
Cracked
Added to basket
£9.99
Paperback
UKCAT For Dummies
Added to basket
£19.99
Paperback
The Story of San Michele
Added to basket
Essential Medical Statistics
Added to basket
Contented Dementia
Added to basket
£14.99
Paperback

Please sign in to write a review

Your review has been submitted successfully.