In the 1980s, capillary electrophoresis (CE) joined high-performance liquid chromatography (HPLC) as the most powerful separation technique available to analytical chemists and biochemists. Published research using CE grew from 48 papers in the year of commercial introduction (1988) to 1200 in 1997. While only a dozen major pharmaceutical and biotech companies have reduced CE to routine practice, the applications market is showing real or potential growth in key areas, particularly in the DNA marketplace for genomic mapping and forensic identification. For drug development involving small molecules (including chiral separations), one CE instrument can replace 10 liquid chromatographs in terms of speed of analysis. CE also uses aqueous rather than organic solvents and is thus environmentally friendlier than HPLC. The second edition of Practical Capillary Electrophoresis has been extensively reorganized and rewritten to reflect modern usage in the field, with an emphasis on commercially available apparatus and reagents. This authoritative and very comprehensible treatment builds on the author's extensive experience as an instructor of short courses for the American Chemical Society and for industry.
Publisher: Elsevier Science Publishing Co Inc
Number of pages: 462
Weight: 740 g
Dimensions: 229 x 152 x 24 mm
Edition: 2nd edition
"The Breadth and depth of this text are appropriate for the growing use of capillary electrophoresis. The book conveys general and fundamental concepts in a readable manner combined with an awareness of the need to sort out practical concerns for implementing capillary electrophoresis." --Lisa Holland, Kent State University, JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, Vol. 123
"...the book is formatted with easy to read text and logically organized information. Most chapters start with a detailed explanation of the CE process and then present many "real-world" examples. Although most of the information and examples are geared toward the industrial use of CE, academic laboratories and graduate students should find the text very helpful." --Jonathan Sweedler, Jason Page, and Zin Zhang, University of Illinois, CE TECHNOLOGIES