Potassium Channels: Methods and Protocols - Methods in Molecular Biology 491 (Paperback)Jonathan D. Lippiat (editor)
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Due to the importance of potassium channels in cellular function, researchers have been challenged to develop tools and experimental procedures to probe the function and identify chemicals that modulate the behaviour of this super-family of ion channels. In Potassium Channels: Methods and Protocols, experts in the field present a range of experimental approaches that have been developed to investigate potassium channel structure, function, pharmacology, cell biology, gene expression, and their role in disease. Many of these techniques study potassium channels as cellular proteins as well as the resultant membrane biophysics. Written in the highly successful Methods in Molecular Biology ™ series format, the chapters contain brief introductions to the subject, lists of the necessary materials and reagents, readily reproducible laboratory protocols, and a Notes section, which highlights tips on troubleshooting and avoiding known pitfalls.
Thorough and cutting-edge, Potassium Channels: Methods and Protocols provides a wide range of approaches in order to aid current research projects and inspire new investigations.
Publisher: Humana Press Inc.
Number of pages: 302
Weight: 764 g
Dimensions: 260 x 193 x 20 mm
Edition: Softcover reprint of hardcover 1st ed. 2009
From the reviews:
"This is a very informative book, covering a variety of methods available to study potassium channels ... . The protocols are clearly organized and usefully detailed. ... Illustrative figures and in some cases, photographs of equipment ... adding to the clarity of the methods sections. This book ... a valuable reference not only for those already in the potassium channel field but also for studies of other ion channel systems. ... each chapter allows bench scientists to undertake new, informed, experimental approaches in their research." (Samantha Miller, Microbiology Today, July, 2009)"This book is dedicated to experimental methods, which allow us to investigate potassium channels from their genes through gene transcription to protein structure, function and regulation in health and disease. ... chapters in this book are written in form of practical laboratory protocols. Therefore the book will be primarily used by practicing scientists and by graduated and post-graduate students for their practical research. Certainly it will find its place in many laboratories investigating various features of potassium channels regulations." (Lubica Lacinova, General Physiology and Biophysics, Vol. 29, April, 2010)