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Phosphodiesterases and Their Inhibitors - Methods and Principles in Medicinal Chemistry (Hardback)Spiros Liras (editor), Andrew S. Bell (editor), Raimund Mannhold (series editor), Hugo Kubinyi (series editor), Gerd Folkers (series editor)
Hardback 240 Pages / Published: 23/04/2014
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Written by the pioneers of Viagra, the first blockbuster PDE inhibitor drug. Beginning with a review of the first wave of phosphodiesterase (PDE) inhibitors, this book focuses on new and emerging PDE targets and their inhibitors. Drug development options for all major human PDE families are discussed and cover diverse therapeutic fields, such as neurological/psychiatric, cardiovascular/metabolic, pain, and allergy/respiratory diseases. Finally, emerging chemotherapeutic applications of PDE inhibitors against malaria and other tropical diseases are discussed.
Publisher: Wiley-VCH Verlag GmbH
Number of pages: 240
Weight: 672 g
Dimensions: 246 x 173 x 18 mm
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