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Pharmacokinetic and Pharmacodynamic Drug Interactions Associated with Antiretroviral Drugs (Hardback)
  • Pharmacokinetic and Pharmacodynamic Drug Interactions Associated with Antiretroviral Drugs (Hardback)
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Pharmacokinetic and Pharmacodynamic Drug Interactions Associated with Antiretroviral Drugs (Hardback)

(editor), (editor), (editor)
£79.00
Hardback 135 Pages / Published: 03/01/2017
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Clinically-focussed, with easily accessible tables and chapter summaries suitable for clinicians and researchers, this comprehensive book provides a systematic, critical evaluation of the current literature. An updated clinical decision-making algorithm specifically tailored to the antiretroviral drugs is also provided. The identified interactions are interpreted in the context of known mechanisms derived from clinical, preclinical, and in vitro data. The clinical relevance of the interactions is systematically evaluated and gaps in literature discussed in the context of potential future experiments. In addition to the comprehensive summary of pharmacokinetic and pharmacodynamic drug interactions associated with WHO-recommended antiretroviral drugs on the market today (i.e. nucleotide reverse-transcriptase inhibitors, non-nucleoside reverse-transcriptase inhibitors, integrase inhibitors, and protease inhibitors), this book also provides detailed section summaries on the epidemiology of HIV infection, diagnosis and pharmacotherapy, basic pharmacology of the individual antiretrovirals, pertinent pre-clinical and in vitro molecular pharmacology, and in vitro drug interaction data available in the literature today.

Publisher: Springer Verlag, Singapore
ISBN: 9789811021121
Number of pages: 135
Weight: 3697 g
Dimensions: 235 x 155 x 15 mm
Edition: 1st ed. 2016


MEDIA REVIEWS
"Antiretrovirals are an unfamiliar topic to most clinicians not already immersed in the field. This is a thorough review of the available literature on each agent used against HIV regarding both their effects on other drugs as well as how other drugs affect them. ... The book is geared towards student/resident learners who would like to understand the intricacies of antiretroviral pharmacokinetics/pharmacodynamics." (David E. Koren, Doody's Book Reviews, March, 2016)

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