Pediatric Formulations: A Roadmap - AAPS Advances in the Pharmaceutical Sciences Series 11 (Hardback)
  • Pediatric Formulations: A Roadmap - AAPS Advances in the Pharmaceutical Sciences Series 11 (Hardback)
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Pediatric Formulations: A Roadmap - AAPS Advances in the Pharmaceutical Sciences Series 11 (Hardback)

(editor), (editor)
£149.99
Hardback 439 Pages / Published: 31/01/2014
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Until the 1990s, it was generally accepted that medicines were first developed for adults and their use in children was investigated later, if at all. One of the main tasks of hospital pharmacies was the manufacturing of child-appropriate formulations in a more or less makeshift way. The first change came in 1997 with U.S. legislation that rewarded manufacturers to do voluntary pediatric research. Ten years later, the European Union passed legislation that required manufacturers to discuss all pediatric aspects, including formulations, with the regulatory authorities as a condition of starting the registration procedure. In consequence, manufacturers must now cover all age groups, including the youngest ones. So far, pediatric formulations were more a focus for academic researchers. Through the changed regulatory environment, there is now a sudden high commercial demand for age-appropriate formulations. This book begins by highlighting the anatomical, physiological and developmental differences between adults and children of different ages. It goes on to review the existing technologies and attempts to draw a roadmap to better, innovative formulations, in particular for oral administration. The regulatory, clinical, ethical and pharmaceutical framework is also addressed.

Publisher: Springer-Verlag New York Inc.
ISBN: 9781489980106
Number of pages: 439
Weight: 903 g
Dimensions: 235 x 155 x 25 mm
Edition: 2014 ed.


MEDIA REVIEWS

From the reviews:

"This book can be useful not only for those in drug development, but also for pharmacists who work in pediatrics (either hospital or community pharmacists), compounding pharmacists, pediatricians, nurses who specialize in this area, and certainly students or residents in any of these disciplines who plan to focus on pediatrics. ... I have reviewed and used many books on drug formulations and pharmaceutics, but I have not seen such a complete book devoted specifically to pediatrics." (Patrick J. McDonnell, Doody's Book Reviews, July, 2014)

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