Pathogenicity Islands and the Evolution of Pathogenic Microbes: Volume I - Current Topics in Microbiology and Immunology 264/1 (Paperback)
  • Pathogenicity Islands and the Evolution of Pathogenic Microbes: Volume I - Current Topics in Microbiology and Immunology 264/1 (Paperback)
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Pathogenicity Islands and the Evolution of Pathogenic Microbes: Volume I - Current Topics in Microbiology and Immunology 264/1 (Paperback)

(editor), (editor)
£149.99
Paperback 234 Pages / Published: 01/12/2010
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It has been known for a number of years that not only pathogenicity islands but also plasmids and bacteriophages are able to carry genes whose products are involved in pathogenic processes. Accordingly, such elements and their products play an important role in pathogenesis due to the intestinal E. coli as well due to Shigellae. Another interesting aspect which is reflected in different articles is that genomes evolve by acquisition of new pieces of DNA following gene transfer, but also by genome reduction. Different mechanisms include the deletion of sequences or the elimination of functions by the accumulation of point mutations or rearrangements.

Publisher: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
ISBN: 9783642076565
Number of pages: 234
Weight: 393 g
Dimensions: 235 x 155 mm
Edition: Softcover reprint of hardcover 1st ed. 2002


MEDIA REVIEWS

From the reviews:

"In addition to classic mutational events, a highly successful strategy of generating genetic diversity in bacteria is the acquisition of genomic islands. ... This compendium ... features an international assembly of authors including W. Arber (Basel) giving a lucid introduction into the evolution of prokaryotic genomes. The two-volume work provides a comprehensive overview of the current state of knowledge on PAIs and other mobile virulence determinants in bacterial as well as fungal pathogens of humans and plants." (Susanne Rohrer, BioWorld, Issue 6, 2002)

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