Neuropilin: From Nervous System to Vascular and Tumor Biology - Advances in Experimental Medicine and Biology 515 (Hardback)
  • Neuropilin: From Nervous System to Vascular and Tumor Biology - Advances in Experimental Medicine and Biology 515 (Hardback)
zoom

Neuropilin: From Nervous System to Vascular and Tumor Biology - Advances in Experimental Medicine and Biology 515 (Hardback)

(editor)
£179.99
Hardback 142 Pages / Published: 31/01/2003
  • We can order this

Usually despatched within 3 weeks

  • This item has been added to your basket
Cell adhesion is one of the most important properties controlling embryonic development. Extremely precise cell-cell contacts are established according to the nature of adhesion molecules that are expressed on the cell surface. The identifica- tion of several families of adhesion molecules, well conserved throughout evolu- tion, has been the basis of a considerable amount of work over the past 20 years that contributed to establish functions of cell adhesion in almost all organs. Nowadays, cell adhesion molecules are not just considered as cellular glue but are thought to play critical roles in cell signaling. Their ability to influence cell proliferation, mi- gration, or differentiation depends on both cell surface adhesion properties and acti- vation of intracellular pathways. The next challenge will be to understand how these molecules interact with each other to ensure specific functions in the morphogen- esis of very sophisticated systems. Indeed, by exploring the cellular and molecular mechanisms of nervous system development, the group of H. Fujisawa in Japan identified in 1987 an adhesion molecule, neuropilin, highly expressed in the neuro- pile of amphibian optic tectum. Ten years later, two groups discovered that neuropilin is a receptor for guidance signals of the semaphorin family. Axon guidance is a critical step during brain development and the mechanisms ensuring growth cone navigation are beginning to be well understood. The semaphorins are bifunctional signals defining permissive or inhibitory pathways sensed by the growth cone.

Publisher: Springer Science+Business Media
ISBN: 9780306474163
Number of pages: 142
Weight: 451 g
Dimensions: 235 x 155 x 15 mm
Edition: 2002 ed.

You may also be interested in...

Emotion: A Very Short Introduction
Added to basket
The Private Life of the Brain
Added to basket
Brain Rules (Updated and Expanded)
Added to basket
This Idea Must Die
Added to basket
BIOS Instant Notes in Neuroscience
Added to basket
Brain Storms
Added to basket
£14.99
Paperback
The Tale of the Duelling Neurosurgeons
Added to basket
The Human Brain Coloring Book
Added to basket
The Autistic Brain
Added to basket
Mind Change
Added to basket
£9.99
Paperback
Incognito
Added to basket
£9.99
Paperback
The Brain: A Very Short Introduction
Added to basket
The Developing Mind, Second Edition
Added to basket
Descartes' Error
Added to basket
£10.99
Paperback
The Future of the Mind
Added to basket

Reviews

Please sign in to write a review

Your review has been submitted successfully.