• Sign In / Register
  • Help
  • Basket0
Neurophenotypes: Advancing Psychiatry and Neuropsychology in the "OMICS" Era - Innovations in Cognitive Neuroscience (Hardback)
  • Neurophenotypes: Advancing Psychiatry and Neuropsychology in the "OMICS" Era - Innovations in Cognitive Neuroscience (Hardback)
zoom

Neurophenotypes: Advancing Psychiatry and Neuropsychology in the "OMICS" Era - Innovations in Cognitive Neuroscience (Hardback)

(editor), (editor)
£109.99
Hardback 306 Pages / Published: 27/02/2017
  • We can order this

Usually despatched within 3 weeks

  • This item has been added to your basket

The interest in `biomarkers' seen across a spectrum of biomedical disciplines reflects the rise of molecular biology and genetics. A host of `omics' disciplines in addition to genomics, marked by multidimensional data and complex analyses, and enabled by bioinformatics, have pushed the trajectory of biomarker development even further. They have also made more tractable the complex mappings of genotypes to phenotypes - genome-to-phenome mapping - to which the concept of a biomarker is central.

Genomic investigations of the brain are beginning to reveal spectacular associations between genes and neural systems. Neural and cognitive phenomics are considered a necessary complement to genomics of the brain. Other major omics developments such as connectomics, the comprehensive mapping of neurons and neural networks, are heralding brain maps of unprecedented detail. Such developments are defining a new era of brain science. And in this new research environment, neural systems and cognitive operations are pressed for new kinds of definitions - that facilitate brain-behavioral alignment in an omics operating environment.

This volume explores the topic of markers framed around the constructs of cognitive and neural systems. `Neurophenotype' is a term adopted to describe a neural or cognitive marker that can be scientifically described within an associative framework - and while the genome-to-phenome framework is the most recognized of these, epigenetics and non-gene-regulated neural dynamics also suggest other frameworks. In either case, the term neurophenotype defines operational constructs of brain-behavioral domains that serve the integration of these domains with neuroscientific and omics models of the brain. The topic is critically important to psychiatry and neuropsychology: Neurophenotypes offer a `format' and a `language' by which psychiatry and neuropsychology can be in step with the brain sciences. They also bring a new challenge to the clinical neurosciences in terms of construct validation and refinement.

Topics covered in the volume include:

Brain and cognition in the omics era
Phenomics, connectomics, and Research Domain Criteria
Circuit-based neurophenotypes, and complications posed by non-gene regulated factors
The legacy of the endophenotype concept - its utility and limitationsVarious potential neurophenotypes of relevance to clinical neuroscience, including ResponseInhibition, Fear Conditioning and Extinction, Error Processing, Reward Dependence and Reward Deficiency, Face Perception, and Language Phenotypes
Dynamic (electrophysiological) and computational neurophenotypes
The challenge of a cultural shift for psychiatry and neuropsychology

The volume may be especially relevant to researchers and clinical practitioners in psychiatry and neuropsychology and to cognitive neuroscientists interested in the intersection of neuroscience with genomics, phenomics and other omics disciplines.

Publisher: Springer-Verlag New York Inc.
ISBN: 9781461438458
Number of pages: 306
Weight: 792 g
Dimensions: 235 x 155 x 19 mm
Edition: 1st ed. 2016

You may also be interested in...

The Biology of Desire
Added to basket
The Art of Loving
Added to basket
£8.99
Paperback
The Organized Mind
Added to basket
£9.99   £7.99
Paperback
Facing Love Addiction
Added to basket
Superhuman
Added to basket
£20.00
Hardback
The Man Who Mistook His Wife for a Hat
Added to basket
The Science of Meditation
Added to basket
Your Conscious Mind
Added to basket
Bored and Brilliant
Added to basket
The Man Who Mistook His Wife for a Hat
Added to basket
The Happy Brain
Added to basket
£12.99   £9.99
Paperback
The Smell of Fresh Rain
Added to basket
Why We Sleep
Added to basket
£20.00
Hardback
Courage
Added to basket
£11.99
Paperback
Molecules Of Emotion
Added to basket

Reviews

Please sign in to write a review

Your review has been submitted successfully.