Your Waterstones card is changing, introducing...
TELL ME MORE
Neural Control of Renal Function - Colloquium Series on Integrated Systems Physiology (Paperback)
  • Neural Control of Renal Function - Colloquium Series on Integrated Systems Physiology (Paperback)
zoom

Neural Control of Renal Function - Colloquium Series on Integrated Systems Physiology (Paperback)

(author)
£38.50
Paperback 96 Pages / Published: 30/12/2010
  • We can order this

Usually despatched within 2 weeks

  • This item has been added to your basket
The kidney is innervated with efferent sympathetic nerve fibers reaching the renal vasculature, the tubules, the juxtaglomerular granular cells, and the renal pelvic wall. The renal sensory nerves are mainly found in the renal pelvic wall. Increases in efferent renal sympathetic nerve activity reduce renal blood flow and urinary sodium excretion by activation of ?1-adrenoceptors and increase renin secretion rate by activation of ?1-adrenoceptors. In response to normal physiological stimulation, changes in efferent renal sympathetic nerve activity contribute importantly to homeostatic regulation of sodium and water balance. The renal mechanosensory nerves are activated by stretch of the renal pelvic tissue produced by increases in renal pelvic pressure of a magnitude that may occur during increased urine flow rate. Activation of the sensory nerves elicits an inhibitory renorenal reflex response consisting of decreases in efferent renal sympathetic nerve activity leading to natriuresis. Increasing efferent sympathetic nerve activity increases afferent renal nerve activity which, in turn, decreases efferent renal sympathetic nerve activity by activation of the renorenal reflexes. Thus, activation of the afferent renal nerves buffers changes in efferent renal sympathetic nerve activity in the overall goal of maintaining sodium balance. In pathological conditions of sodium retention, impairment of the inhibitory renorenal reflexes contributes to an inappropriately increased efferent renal sympathetic nerve activity in the presence of sodium retention. In states of renal disease or injury, there is a shift from inhibitory to excitatory reflexes originating in the kidney. Studies in essential hypertensive patients have shown that renal denervation results in long-term reduction in arterial pressure, suggesting an important role for the efferent and afferent renal nerves in hypertension.

Publisher: Morgan & Claypool Publishers
ISBN: 9781615042319
Number of pages: 96
Weight: 178 g
Dimensions: 235 x 187 x 4 mm

You may also be interested in...

Strength Training Anatomy
Added to basket
The Physiology Coloring Book
Added to basket
Renal Pathophysiology
Added to basket
The Story of the Human Body
Added to basket
The Music of Life
Added to basket
£8.99
Paperback
Anatomies
Added to basket
Holistic Anatomy
Added to basket
£15.99
Paperback
Anatomy & Physiology Made Incredibly Easy!
Added to basket
The Universe Inside You
Added to basket
Muscle Energy Techniques
Added to basket

Reviews

Please sign in to write a review

Your review has been submitted successfully.