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Myeloid Leukemia - Methods in Molecular Biology No. 125 (Paperback)
  • Myeloid Leukemia - Methods in Molecular Biology No. 125 (Paperback)
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Myeloid Leukemia - Methods in Molecular Biology No. 125 (Paperback)

(editor), (editor), (editor)
£66.99
Paperback 320 Pages / Published: 01/08/2009
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A panel of internationally recognized research scientists and clinical investigators brings together a diverse collection of readily reproducible methods for identifying and quantifying a large number of specific genetic abnormalities associated with the broad spectrum of myeloid malignancies. Highlights include techniques for the detection of BCR-ABL mutations and resistance to imatinib mesylate, detection of the FIP1L1-PDGFRA fusion in idiopathic hypereosinophilic syndrome and chronic eosinophilic leukemia, classification of AML by DNA-oligonucleotide microarrays, and detection of the V617F JAK2 mutation in myeloproliferative disorders. In addition to gene rearrangments, other prognostically relevant molecular lesions such as FLT3 mutations and WT-1 overexpression are covered.

Publisher: Humana Press Inc.
ISBN: 9781607614562
Number of pages: 320
Edition: 2006. 2nd Printing ed.

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