Multifunctional Pharmaceutical Nanocarriers - Fundamental Biomedical Technologies 4 (Hardback)
  • Multifunctional Pharmaceutical Nanocarriers - Fundamental Biomedical Technologies 4 (Hardback)
zoom

Multifunctional Pharmaceutical Nanocarriers - Fundamental Biomedical Technologies 4 (Hardback)

(editor)
£179.99
Hardback 474 Pages / Published: 19/05/2008
  • We can order this

Usually dispatched within 3 weeks

  • This item has been added to your basket
The use of various pharmaceutical carriers to enhance the in vivo efficiency of many drugs and drug administration protocols has been well established during the last decade in both pharmaceutical research and clinical setting. Surface modification of pharmaceutical nanocarriers, such as liposome, micelles, na- capsules, polymeric nanoparticles, solid lipid particles, and niosomes, is normally used to control their biological properties in a desirable fashion and to simulta- ously make them perform various therapeutically or diagnostically important functions. The most important results of such modification include an increased stability and half-life of drug carriers in the circulation, required biodistribution, passive or active targeting into the required pathological zone, responsiveness to local physiological stimuli, and ability to serve as contrast agents for various imaging modalities (gamma-scintigraphy, magnetic resonance imaging, computed tomography, ultra-sonography). Frequent surface modifiers (used separately or simultaneously) include soluble synthetic polymers (to achieve carrier longevity); specific ligands, such as antibodies, peptides, folate, transferrin, and sugar moieties (to achieve targeting effect); pH- or temperature-sensitive lipids or polymers (to impart stimuli sensitivity); chelating compounds, such as EDTA, DTPA, and deferoxamine (to add a heavy metal-based diagnostic/contrast moiety onto a drug carrier). Certainly, new or modified pharmaceutical carriers (nanocarriers) as well as their use for the delivery of various drugs and genes are still described in many publications.

Publisher: Springer-Verlag New York Inc.
ISBN: 9780387765518
Number of pages: 474
Weight: 890 g
Dimensions: 235 x 155 x 26 mm
Edition: 2008 ed.

You may also be interested in...

Reviews

Please sign in to write a review

Your review has been submitted successfully.