Molecular mechanisms and physiology of disease: Implications for Epigenetics and Health (Paperback)
  • Molecular mechanisms and physiology of disease: Implications for Epigenetics and Health (Paperback)
zoom

Molecular mechanisms and physiology of disease: Implications for Epigenetics and Health (Paperback)

(editor), (editor)
£139.99
Paperback 505 Pages / Published: 17/09/2016
  • We can order this

Usually dispatched within 3 weeks

  • This item has been added to your basket

In a simplified form, epigenetics refers to heritable changes in phenotype that are not due to changes in the underlying DNA sequence. In this book, epigenetic mechanisms of regulation and dysregulation in health and disease are explored in great depth. Detailed chapters on epigenetic processes including DNA methylation and chromatin post-translational modifications including potential interventions with DNA methyltransferase inhibitors and histone deacetylase inhibitors are explored in initial chapters. These provide a detailed overview and important background to the entire field. The book is then focussed on epigenetic mechanisms involved in various diseases including anti-inflammatory and autoimmune conditions. Important accounts relating to the effects of epigenetics in metabolic syndrome, cardiovascular disease and asthma are the focus of subsequent chapters. The role of epigenetic dysregulation in malignancy is a current topic of interest and represents an intense field of research. A large component of this book is dedicated to the analysis of aberrant epigenetic processes in carcinogenesis and cancer progression. Further, chapters are focused on emerging cancer prevention using nutritional components and anti-cancer therapies particularly with histone deacetylase inhibitors, which have already been approved for the treatment of cutaneous T-cell lymphoma. The emerging role of nanoparticle preparations, especially in the context of delivering potential epigenetic therapies to target cells in various diseases, is also explored in this book. Overall, this book encompasses a wide range of topics related to epigenetic mechanisms in health and disease and would appeal to anyone with an interest in epigenetics, chromatin biology and emerging epigenetic interventions and therapies.

Publisher: Springer-Verlag New York Inc.
ISBN: 9781493946235
Number of pages: 505
Weight: 7781 g
Dimensions: 235 x 155 x 27 mm
Edition: Softcover reprint of the original 1st ed. 201

You may also be interested in...

Bonk
Added to basket
£9.99
Paperback
The Music of Life
Added to basket
£8.99
Paperback
Strength Training Anatomy
Added to basket
The Physiology Coloring Book
Added to basket
The Story of the Human Body
Added to basket
Exercise Physiology
Added to basket
Physical Activity and Health
Added to basket
Run, Swim, Throw, Cheat
Added to basket
Anatomy and Physiology in Healthcare
Added to basket
Nursery All About Me
Added to basket
Hormones: A Very Short Introduction
Added to basket

Reviews

Please sign in to write a review

Your review has been submitted successfully.