• Sign In / Register
  • Help
  • Basket0
Modulation of MHC Antigen Expression and Disease (Paperback)
  • Modulation of MHC Antigen Expression and Disease (Paperback)

Modulation of MHC Antigen Expression and Disease (Paperback)

(editor), (editor), (editor)
Paperback 460 Pages / Published: 03/11/2005
  • Not available

This product is currently unavailable.

  • This item has been added to your basket
The major histocompatibility complex (MHC) genes are involved in the immune system's response to tumour and infected cells and in generating an immune response. This book brings together basic aspects of the regulation of MHC antigens with important clinical applications (in viral infection, viral oncology, cancer biology and autoimmunity). There is a strong emphasis on situations where MHC expression is modulated (either stimulated or repressed). The book's major themes are: the mechanisms of MHC expression explored at several levels including the transcription and translation of MHC genes and the insertion of MHC protein molecules into plasma membranes; the effect of cytokines on MHC expression both in the aetiology of certain diseases and in possible immunotherapeutic approaches to disease; and the use of gene therapy to modify MHC expression in cancer cells, and thereby cause tumour rejection.

Publisher: Cambridge University Press
ISBN: 9780521499217
Number of pages: 460
Weight: 640 g
Dimensions: 228 x 152 x 24 mm

'This book is a superb summary of current understanding by some of the leading investigators.' David R. Johnson, BMJ
'... an excellent book which all immunologists should not only read but also buy, because of all the important information collected therein.' R. Wegmann, Cellular and Molecular Biology
'... for individuals interested in MHC biology in health and in disease, this book provides a timely and up-to-date review.' Alice Gottlieb, The Lancet
'... this book can be recommended as an excellent starting point for anyone who wishes to explore the field of MHC expression.' Stephen H. Powis, Immunology Today
' ... valuable.' SGM Quarterly
'... an indispensable reference for researchers and students in cell, developmental, and molecular biology and allied disciplines'. Anticancer Research

You may also be interested in...

A Dictionary of Biology
Added to basket
Dazzled and Deceived
Added to basket
Principles of Development
Added to basket
On Growth and Form
Added to basket
Life's Vital Link
Added to basket
Cells to Civilizations
Added to basket


Please sign in to write a review

Your review has been submitted successfully.