Methods in Membrane Biology: Volume 7 (Paperback)
  • Methods in Membrane Biology: Volume 7 (Paperback)
zoom

Methods in Membrane Biology: Volume 7 (Paperback)

(author)
£76.50
Paperback 267 Pages / Published: 31/07/2013
  • We can order this

Usually dispatched within 3 weeks

  • This item has been added to your basket
The contributions of electron microscopy to membrane biology have been indispensable and, at the same time, disappointing. Membranes were known to exist before the advent of electron microscopy and general principles of their composition and molecular organization had been deduced from permeability and electrical conductivity measurements, polarized light microscopy, and X-ray diffraction. On the other hand, the complexities of the many intracellular membranes and membranous organelles were really not suspected until they were observed by the electron microscopist. One then had further hopes that the high resolution of the electron microscope (theoretically it can resolve atomic distances) would allow the visualization of the molecular architecture of membranes and lead directly to an under- standing of structure and function at the molecular level. This expectation has been largely unrealized. Because of the great difficulties encountered in the preparation of biological material, because of the uncertainty of the chemistry of "staining," and because of numerous electron optical artifacts, it has been a major challenge just to rationalize the observed images in terms of the known facts, let alone to utilize the images to expand our knowledge of the molecular structure of biological membranes. The many differences among membranes with respect to function and composition are lost in the universal trilamellar image. Perhaps the one major exception to this, and the major structural contribution of electron microscopy at the molecular level, has come from freeze-etch electron microscopy.

Publisher: Springer-Verlag New York Inc.
ISBN: 9781475758221
Number of pages: 267
Weight: 425 g
Dimensions: 229 x 152 x 15 mm

You may also be interested in...

The Elements of Murder
Added to basket
Thrive in Biochemistry and Molecular Biology
Added to basket
Genetic Analysis
Added to basket
£58.99
Paperback
Biochemistry
Added to basket
£32.99
Paperback
Biochemistry Demystified
Added to basket
Medical Biochemistry at a Glance
Added to basket
Ecological Biochemistry
Added to basket
How Proteins Work
Added to basket
Pain-Free Biochemistry
Added to basket
Oxford Handbook of Medical Sciences
Added to basket
Clinical Biochemistry
Added to basket
£31.99
Paperback
The Cell: A Very Short Introduction
Added to basket
Chemistry for the Biosciences
Added to basket
BIOS Instant Notes in Biochemistry
Added to basket
Biochemistry For Dummies
Added to basket

Please sign in to write a review

Your review has been submitted successfully.