The understanding of cellular signalling - in eukaryotes mainly carried out by reversible protein phosphorylation - depends on knowledge of the three-dimensional structure of signalling molecules, or proteins. Many aspects of proteins at the atomic level are discussed, such as advances in the determination of protein structure by X-ray diffraction methods, spectroscopial studies, and time-resolved Fourier transform (FTIR) spectroscopy. An area in which a quantum step in the development has occurred is the characterization of a single motor neurone, myosin. The application of laser traps is available to assay the activity of a single motor molecule.
Publisher: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Weight: 580 g
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