Immobilised Living Cell Systems: Modelling and Experimental Methods (Hardback)

This monograph describes the quantitative model-based approach to working with immobilized living cell systems. It provides a comprehensive guide to the practical techniques and mathematical modelling required for their analysis and design. The work summarizes the fundamental principles of mass transfer, modelling and reactors; outlines experimental techniques; and illustrates the applications of immobilized living cell systems with detailed examples. These selected examples highlight problems which may be encountered, explain how to observe a fully functional cell system with minimum disturbance, and discuss the complexities of monitoring and analyzing cell aggregates in comparison to free cells. Furthermore, the case studies cover diverse uses, from waste water treatment, fermentation and ecological systems to artificial organs for biomedicine.