Human Papillomavirus (HPV)-Associated Oropharyngeal Cancer (Hardback)
  • Human Papillomavirus (HPV)-Associated Oropharyngeal Cancer (Hardback)
zoom

Human Papillomavirus (HPV)-Associated Oropharyngeal Cancer (Hardback)

(editor), (editor)
£139.99
Hardback 314 Pages / Published: 11/08/2015
  • We can order this

Usually dispatched within 3 weeks

  • This item has been added to your basket

Head and neck squamous cell carcinoma (HNSCC), the sixth most prevalent cancer worldwide, remains a very difficult disease to treat and cure despite intensive investigation into molecular etiologies and tumor progression pathways. Due to public health efforts encouraging smoking cessation, the overall incidence of HNSCC has decreased in recent years in many countries. In contrast, the incidence of oropharyngeal squamous cell carcinoma (OPSCC) has increased significantly, and this subtype of HNSCC is commonly associated with human papillomavirus (HPV) infection. Moreover, individuals with HPV-positive OPSCC are generally younger and are frequently non-smokers, suggesting that HPV-associated OPSCC represents a distinct biologic entity.

This volume summarizes the spectrum of current HPV-associated OPSCC research from the fundamental basic science to translational surgery and treatment approaches. Chapters are contributed by authoritative leaders in the fields of research and clinical care. Initial chapters address epidemiology, behavioral correlates of HPV infection, and racial disparities in oropharyngeal cancer. This is followed by chapters detailing HPV virology with focus on viral transformation, viral replication, and host response to viral infection. The molecular biology of HPV-associated OPSCC is investigated in chapters detailing alterations in signaling networks and unique mutational profiles of human tumors. Clinical presentation, surgical perspectives, and treatment paradigms specific to HPV-associated OPSCC conclude the volume. This comprehensive volume provides an up-to-date overview of both scientific discovery and clinical management of this emerging public health problem.

Publisher: Springer International Publishing AG
ISBN: 9783319210995
Number of pages: 314
Weight: 6092 g
Dimensions: 235 x 155 x 19 mm
Edition: 1st ed. 2015

You may also be interested in...

Coping with Chemotherapy
Added to basket
Radical Remission
Added to basket
Survival Lessons
Added to basket
Beating Cancer with Nutrition
Added to basket
The Biology of Cancer
Added to basket
B is for Breast Cancer
Added to basket
Added Time
Added to basket
£6.99
Paperback
Practical Radiotherapy Planning
Added to basket
Cancer Care
Added to basket
£7.99
Paperback
Laws of Medicine
Added to basket
Cancer: A Very Short Introduction
Added to basket
Cancer
Added to basket
£12.50
Paperback
Oxford Handbook of Clinical Haematology
Added to basket
£34.99
Part-work (fascículo)
The Cancer Survivor's Companion
Added to basket

Reviews

Please sign in to write a review

Your review has been submitted successfully.