Characteristic of the heat shock or stress response is the synthesis of a family of fairly well-conserved proteins of various molecular sizes - the heat-shock proteins. This volume reviews the evidence that the expression of heat-shock proteins may interact with lymphocytes that bear the gamma-delta T cell receptor and result in the initiation of immunopathology. The possibility that this subset of lymphocytes is specialized to respond to heat-shock proteins has recently generated much interest. The material presented in this volume addresses the question from a pathological perspective. Particular emphasis is placed on studies that have examined human diseases where tissue damage is quite widespread.
Publisher: S Karger AG
Number of pages: 132
Weight: 390 g
Dimensions: 216 x 138 mm
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