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Hairy-Cell Leukaemia - Recent Results in Cancer Research 72 (Hardback)
  • Hairy-Cell Leukaemia - Recent Results in Cancer Research 72 (Hardback)
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Hairy-Cell Leukaemia - Recent Results in Cancer Research 72 (Hardback)

(author), (author), (author)
£72.00
Hardback 123 Pages / Published: 27/06/1980
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Hairy-cell leukaemia (HCL) is an established clinicopathological entity typified by a chronic picture of substantial splenomegaly, less frequent hepatomegaly, and only inconspicuous lymphadenopathy. Central to the diagnosis is the pathognomonic hairy cell (HC), a dis- tinctive mononuclear cell that circulates in varying numbers and infiltrates a variety of organs, including the bone marrow and spleen. Peripheral pancytopenia is often present, and circulating HCs may be infrequent. HCs are invariably present in the bone marrow; but, per- haps because of the extensive fibrosis characteristic of the disease, the marrow is frequently difficult to aspirate, and confirmation of the diagnosis may require histopathological ex- amination of biopsy material. The incidence of the disease has been given as 2% ofleukaemias [29, 319] or as approximately 1 % of identifiable lymphomas [230]. Our own experience of collecting cases in the United Kingdom leads us to expect that at any given time one patient with HCL will be attending a clinic serving some 150,000 people.

Publisher: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
ISBN: 9783540099208
Number of pages: 123
Weight: 400 g

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