Genetics of Diabetes Mellitus - Endocrine Updates 10 (Paperback)William L. Lowe (editor)
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A description of basic concepts of the genetics of complex diseases like type 1 and type 2 diabetes is provided as background. Type 1 diabetes is addressed in chapters exploring genetic determinants that affect the autoimmune process characteristic of type 1 diabetes, the role of the insulin gene in the pathogenesis of type 1 diabetes and additional genes that may impact upon the risk of type 1 diabetes. The impact of genetic determinants on the pathophysiology of type 2 diabetes is covered, as are chapters that address specific genes that are important for the development of type 2 diabetes. Finally, syndromic forms of diabetes, including Maturity Onset Diabetes of the Young and mitochondrial diabetes, and the insight that these disorders provide into more common forms of diabetes are reviewed.
Thus, this comprehensive and up-to-date text will serve as an important resource for those actively engaged in research in this area and clinicians treating these patients to provide an up-to-date entree for those seeking to become more knowledgeable in the area.
Publisher: Springer-Verlag New York Inc.
Number of pages: 255
Weight: 415 g
Dimensions: 235 x 155 x 14 mm
Edition: Softcover reprint of the original 1st ed. 200