Gene Therapy - NATO ASI Series H: Cell Biology Vol 105 (Hardback)K. Xanthopoulos (editor)
Hardback Published: 20/05/1998
- Not available
The succesful introduction of a gene sequence in somatic cells followed by long-term expression at therapeutic levels can fundamentally correct a variety of inherited and acquired diseases. Therefore gene therapy holds great promise in the field of clinical and molecular medicine. This volume summarizes recent advances in the field. It emphasizes the influence of chromatin structure on gene expression, describes the the principal mechanisms of gene expression, epigenic elements, viral vectors, non-viral vectors as gene delivery systems, animal models of human diseases, inducible regulatory systems, gene therapy of cancer, AIDS, monogenic disorders, and ongoing clinical trials.
Publisher: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Weight: 550 g
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