Accumulating evidence suggests that oxidative and nitrosative stress plays a major role in the initiation and progression of Alzheimer's disease. In this monograph, the role of oxygen- and nitrogen-centred radicals in the pathogenesis of the disease is examined in depth. Detailed attention is also paid to the use of free radical scavengers as prophylactic agents and the potential therapeutic role of iron and copper chelators. The author's own research is complemented by an exhaustive analysis of the relevant literature, with the citation of more than 9000 publications. "Free Radicals and Alzheimer's Disease" will be a fascinating and invaluable source of information for researchers and clinicians.
Publisher: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG ISBN: 9783642318054 Number of pages: 1029 Dimensions: 254 x 178 mm Edition: 2014 ed.
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