Feedback Mechanisms in Blood Coagulation and Their Inhibition by Heparins: Special Topic Issue: Pathophysiology of Haemostasis and Thrombosis 1991, Vol. 21, No. 4 (Paperback)H. C. Hemker (editor)
Paperback 88 Pages / Published: 10/12/1991
- Not available
This publication concentrates on the regulatory aspects of thrombin generation. Thrombin generation is an important process which is central to haemostasis and thrombosis. This unique biochemical system involves the proteolytic activation and inactivation of enzymes together with reactions at interfaces and non-enzymatic protein co-factors. The importance of the understanding of the influences of antithrombotic drugs on the mechanism cannot be overestimated, given the fact that some form of thrombosis (coronary infaction, stroke, pulmonary embolisms) accounts for almost half of the deaths occurring in the Western population. Both of biochemical and medical interest, the publication provides an overview of the role of feedback activation and inhibition as well as issues involved in therapeutic intervention.
Publisher: S Karger AG
Number of pages: 88
Weight: 220 g
Dimensions: 216 x 138 mm
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