The first edition of this highly acclaimed reference work was published in 1980. Since then no other book has approached the breadth, scholarship and the balance of this book. For this long-awaited second edition, the original editors have been joined by Albert Ludolph, who brings in expertise in biological neurotoxicology.
In the introductory chapters, an overview of the biological basis of neurotoxicity provides the groundwork for discussing the scope of human and veterinary neurotoxic disease. The bulk of the text is devoted to an encyclopaedic treatment of chemicals with neurotoxic potential. This consists of tightly written overviews of the properties, actions and mechanisms of all manner of substances, whether natural or synthetic. The neurotoxic mechanisms of experimental agents and adverse effects of
therapeutic and abused drugs are covered extensively. Environmental pollutants, workplace contaminants, personal-use products, food additives and agents harboured by plants, animals and humans for use against their respective enemies are all included. Each substance is rated on a three-point scale for the
weight of evidence indicating a specific neurotoxic effect in humans, animals, or laboratory models. These effects are summarised and cross-referenced in a series of appendices and an extensive index.
This book will be indispensable to experimental neuroscientists, toxicologists, and practitioners of human and animal medicine. It also provides an authoritative, critical and pithy reference work for public health specialists and those within the legal profession.
Publisher: Oxford University Press Inc
Number of pages: 1350
Weight: 3338 g
Dimensions: 285 x 222 x 67 mm
Edition: 2nd Revised edition
From reviews of the first edition: "... impact of synthesizing and consolidating a whole body of knowledge so as to literally create and legitimize a new field in clinical neurology ... a brilliant new beacon on the horizon ... a comprehensive and scholarly statement of current knowledge ... an indispensable map for anyone planning in these charted or unchartered waters ... this book will soon join the esteemed rank of now classic books ... by such persons as H.
Houston Merritt, Goodman and Cecil and Loeb, Lehninger and even Rachel Carson - Neurology