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Excited States and Free Radicals in Biology and Medicine: Contributions from Flash Photolysis and Pulse Radiolysis (Hardback)
  • Excited States and Free Radicals in Biology and Medicine: Contributions from Flash Photolysis and Pulse Radiolysis (Hardback)

Excited States and Free Radicals in Biology and Medicine: Contributions from Flash Photolysis and Pulse Radiolysis (Hardback)

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Hardback 448 Pages / Published: 16/09/1993
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Excited states and free radicals are involved in the normal physiology of living systems; in pathological processes including lipid peoxidation, inflammation, Parkinson's disease, cancer, and ageing; in the mechanism of action of drugs, such as quinone antitumour agents, and in the photochemotherapies such as the PUVA therapy of skin diseases and PDT of cancer. The chief aim of this text is to introduce the reader to this rapidly expanding field, which lies at the borderlines of physics, chemistry, biology, pharmacology, and medicine, and, in particular, to explore how time-resolved spectroscopic methods have found solutions at the molecular level to biological and medical problems. In the first three chapters, the nature of excited states and free radicals, and the fast kinetic and spectroscopic techniques for their study are described. Amongst the biological areas described in the subsequent chapters are: activated oxygen species; DNA; proteins; carotenoids and photosynthetic reaction centres; photodermatology and melanogenesis; and aspects of cancer related to radio-, chemo-, and photodynamic therapy.

Publisher: Oxford University Press
ISBN: 9780198555605
Number of pages: 448
Weight: 858 g
Dimensions: 234 x 156 x 30 mm

'I recommend this book to both specialists and non-specialists who are interested in knowing more about the molecular basis of biological problems: it is comprehensive, easy to read and competitively priced. The authors should be commended, in my opinion, in having achieved their goal, on the whole, of preparing a text which should be useful to students, research scientists and clinicians who are interested in gaining a deeper appreciation of the molecular aspects of biological problems.' Peter O'Neill, Melanoma Research, Vol. 4, 1994
contains a considerable amount of useful information ... It is well written ... very pleasant and interesting to read ... Students, researchers, and also physicians ... will find competently written introductions to the field, a large amount of interesting information, both on basic research and applications, and a detailed bibliography. * Ester Oliveros and Andre M. Braun, Universitat Karlsruhe, Journal of Photochemistry and Photobiology B: Biology 26 (1994) 103 *

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