Visit our Christmas Gift Finder
Emerging Concepts Targeting Immune Checkpoints in Cancer and Autoimmunity - Current Topics in Microbiology and Immunology 410 (Hardback)
  • Emerging Concepts Targeting Immune Checkpoints in Cancer and Autoimmunity - Current Topics in Microbiology and Immunology 410 (Hardback)
zoom

Emerging Concepts Targeting Immune Checkpoints in Cancer and Autoimmunity - Current Topics in Microbiology and Immunology 410 (Hardback)

(editor)
£149.99
Hardback 267 Pages / Published: 13/12/2017
  • We can order this

Usually dispatched within 3 weeks

  • This item has been added to your basket

This volume reviews the current state of research on immune checkpoints and offers novel concepts. It discusses the two most important immune checkpoints: T lymphocyte-associated antigen-4 (CTLA-4) and programmed cell death-1 (PD-1). It shows that antagonistic antibodies against these two molecules are highly effective in the treatment of various cancers and that PD-1 and CTLA-4 have been linked to the suppression of T-cell receptor signaling and co-stimulatory molecules. Further, the volume examines other agents, a number of cells, receptors and signaling molecules, that are also involved in the regulation of T-cell activation and extends the concept of immune checkpoints to "molecules and cells that negatively regulate T-cell activation". Playing essential roles in immune homeostasis, they could offer new targets for cancer immunotherapy, and for the therapy of autoimmune diseases.

Written by internationally respected scientists, this book will appeal to basic scientists, clinicians, drug development researchers, and advanced students alike.

Publisher: Springer International Publishing AG
ISBN: 9783319689289
Number of pages: 267
Weight: 5384 g
Dimensions: 235 x 155 mm
Edition: 1st ed. 2017

You may also be interested in...

Oxford Handbook of Oncology
Added to basket
£34.99
Part-work (fascículo)
Improvising Medicine
Added to basket
The Biology of Cancer
Added to basket
Beat Cancer
Added to basket
£14.99
Paperback
The End of Your Life Book Club
Added to basket
Cancer Virus
Added to basket
Cancer Care
Added to basket
£7.99
Paperback
Medicine Hands
Added to basket
£29.99
Paperback
The Cancer-Fighting Diet
Added to basket
The Cancer Survivor's Companion
Added to basket
Beating Cancer with Nutrition
Added to basket
Radical Remission
Added to basket

Please sign in to write a review

Your review has been submitted successfully.