Dual-Mode Electro-photonic Silicon Biosensors - Springer Theses (Hardback)
  • Dual-Mode Electro-photonic Silicon Biosensors - Springer Theses (Hardback)
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Dual-Mode Electro-photonic Silicon Biosensors - Springer Theses (Hardback)

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Hardback 149 Pages / Published: 27/07/2017
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This highly interdisciplinary thesis reports on two innovative photonic biosensors that combine multiple simultaneous measurements to provide unique insights into the activity and structure of surface immobilized biological molecules. In addition, it presents a new silicon photonic biosensor that exploits two cascaded resonant sensors to provide two independent measurements of a biological layer immobilized on the surface. By combining these two measurements, it is possible to unambiguously quantify the density and thickness of the molecular layer; here, the approach's ability to study molecular conformation and conformational changes in real time is demonstrated.
The electrophotonic biosensor integrates silicon photonics with electrochemistry into a single technology. This multi-modal biosensor provides a number of unique capabilities that extend the functionality of conventional silicon photonics. For example, by combining the complementary information revealed by simultaneous electrochemical and photonic measurements, it is possible to provide unique insights into on-surface electrochemical processes. Furthermore, the ability to create electrochemical reactions directly on the silicon surface provides a novel approach for engineering the chemical functionality of the photonic sensors. The electrophotonic biosensor thus represents a critical advance towards the development of very high-density photonic sensor arrays for multiplexed diagnostics.

Publisher: Springer International Publishing AG
ISBN: 9783319605005
Number of pages: 149
Weight: 474 g
Dimensions: 235 x 155 mm
Edition: 1st ed. 2017

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