Visit our Christmas Gift Finder
Combinatorial Peptide Library Protocols - Methods in Molecular Biology 87 (Hardback)
  • Combinatorial Peptide Library Protocols - Methods in Molecular Biology 87 (Hardback)
zoom

Combinatorial Peptide Library Protocols - Methods in Molecular Biology 87 (Hardback)

(editor)
£127.50
Hardback 313 Pages / Published: 23/12/1997
  • We can order this

Usually dispatched within 3 weeks

  • This item has been added to your basket
During the course of evolution, an imbalance was created between the rate of vertebrate genetic adaptation and that of the lower forms of living organisms, such as bacteria and viruses. This imbalance has given the latter the advantage of generating, relatively quickly, molecules with unexpected structures and features that carry a threat to vertebrates. To compensate for their weakness, vertebrates have accelerated their own evolutionary processes, not at the level of whole organism, but in specialized cells containing the genes that code for antibody molecules or for T-cell receptors. That is, when an immediate requirement for molecules capable of specific interactions arose, nature has preferred to speed up the mode of Darwinian evolution in pref- ence to any other approach (such as the use of X-ray diffraction studies and computergraphic analysis). Recently, Darwinian rules have been adapted for test tube research, and the concept of selecting molecules having particular characteristics from r- dom pools has been realized in the form of various chemical and biological combinatorial libraries. While working with these libraries, we noticed the interesting fact that when combinatorial libraries of oligopeptides were allowed to interact with different selector proteins, only the actual binding sites of these proteins showed binding properties, whereas the rest of the p- tein surface seemed "inert. " This seemingly common feature of protein- having no extra potential binding sites--was probably selected during evolution in order to minimize nonspecific interactions with the surrounding milieu.

Publisher: Humana Press Inc.
ISBN: 9780896033924
Number of pages: 313
Weight: 721 g
Dimensions: 235 x 155 x 26 mm
Edition: 1998 ed.

You may also be interested in...

Hormones: A Very Short Introduction
Added to basket
Chemistry for the Biosciences
Added to basket
The Cell: A Very Short Introduction
Added to basket
Genetic Analysis
Added to basket
£55.99
Paperback
Color Atlas of Biochemistry
Added to basket
Molecular Biology
Added to basket
£54.99
Paperback
Biochemistry Demystified
Added to basket
Fundamentals of Biochemical Calculations
Added to basket
Mathematics for Biological Scientists
Added to basket
Oxford Handbook of Medical Sciences
Added to basket
£29.99
Part-work (fascículo)
Immunology
Added to basket
£18.99
Paperback
Biochemistry For Dummies
Added to basket
The Chemistry of Life
Added to basket
Pain-Free Biochemistry
Added to basket

Reviews

Please sign in to write a review

Your review has been submitted successfully.