Clinical Use of Antiviral Drugs - Developments in Medical Virology 3 (Hardback)
  • Clinical Use of Antiviral Drugs - Developments in Medical Virology 3 (Hardback)
zoom

Clinical Use of Antiviral Drugs - Developments in Medical Virology 3 (Hardback)

(editor)
£199.99
Hardback 414 Pages / Published: 31/01/1988
  • We can order this

Usually dispatched within 3 weeks

  • This item has been added to your basket
Antiviral chemotherapy has come of age, and, after an initial slow pro- gress, the development of new antiviral agents has proceeded at a more rapid pace and the perspectives for their clinical use have increased considerably. Now, 25 years after the first antiviral assay (idoxuridine) was introduced in the clinic, it is fitting to commemorate the beginning of the antivirals' era. In its introductory chapter B.E. Juel-Jensen touches on what may be con- sidered as five of the most fundamental requirements of an antiviral drug : efficacy, relative non-toxicity, easy solubility, ready availability and rea- sonable cost. Surely, the antiviral drugs that have so far been used in the clinic could still be improved upon as one or more of these five essential demands are concerned. How is all began is narrated by W.H. Prusoff. The first antiviral drugs to be used in humans were methisazone and idoxuridine, the former, which is now of archival interest, in the prevention of smallpox, the latter, which was approved for clinical use in the United States in 1962, for the topical treatment of herpetic keratitis. In terms of potency, also because of solubility reasons, idoxuridine has been superseded by trifluridine in the topical treatment of herpes simplex epithelial keratitis. H.E. Kaufman did not find trifluridine or acyclovir ef- fective in the treatment of deep stromal keratitis or iritis and he reckons that other antiviral drugs (i.e. bromovinyldeoxyuridine) would not be effec- tive either.

Publisher: Kluwer Academic Publishers
ISBN: 9780898383577
Number of pages: 414
Weight: 1730 g
Dimensions: 235 x 155 x 23 mm
Edition: 1988 ed.

You may also be interested in...

The Invisible Enemy
Added to basket
A Dictionary of Forensic Science
Added to basket
Missing Microbes
Added to basket
£8.99
Paperback
Oxford Handbook of Medical Sciences
Added to basket
£29.99
Part-work (fascículo)
Ebola
Added to basket
£5.99
Paperback
Oxford Handbook of Clinical Surgery
Added to basket
£29.99
Part-work (fascículo)
Essentials of Pathophysiology
Added to basket
Killer Germs
Added to basket
£14.99
Paperback
Candida Albicans
Added to basket
£9.99
Paperback
Diagnostic Dermoscopy
Added to basket

Reviews

Please sign in to write a review

Your review has been submitted successfully.