Clinical Trials of Genetic Therapy with Antisense DNA and DNA Vectors (Hardback)Eric Wickstrom (editor)
- Not available
Combining the insights of over 50 contributors, Clinical Trials of Genetic Therapy with Antisense DNA and DNA Vectors
furnishes a historical overview of genetic therapy
highlights official Food and Drug Administration positions on the preparation of oligonucleotides and vectors
offers practical models of agent preparation, animal testing, pharmacokinetics, toxicology, and clinical trials
discusses both synthetic DNA and biological vector approaches to cancer, viral, and cardiological indications
illustrates for new practitioners how each stage of genetic therapy is developed
details genetic treatment of leukemia; lymphoma; cancer of the brain, breast, colon, kidney, and lung; melanoma; HIV; and coronary restenosis
includes examples of antisense, ribozyme, tumor suppressor, immunostimulation, and gene replacement therapy
and addresses questions of preparation, delivery, toxicity, mechanism, and specificity.
Publisher: Taylor & Francis Inc
Number of pages: 448
Weight: 953 g
Dimensions: 279 x 216 x 25 mm
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