This is a comprehensive handbook on all aspects of adverse effects by drugs, chemical substances and radiation on the kidneys. The book consists of a general part dealing with themes such as clinical relevance, renal handling and cellular mechanisms of nephrotoxicity, as well as animal and cell culture models. The second part includes the specific drugs, for instance the anti-infectious agents, anti-inflammatory drugs, cardiovascular drugs, anti-cancer drugs and so forth. The last part deals with the prevention consisting of urinary biomarkers, pharmacological aspects and drug dosage in renal failure. In this second and completely revised edition, several new topics were added, information regarding the paediatric age group was expanded and up-to-date references provided, while remaining true to the concept of a multinational author book.
Publisher: Kluwer Academic Publishers