Interaction of antigen antibody complexes with cells via specific immunoglobulin Fc receptors (FcR) triggers major immunological reactions, such as efficient uptake of antigen, phagocytosis of microorganisms, cytotoxicity towards tumour- or virus-infected cells, and mast cell derangulation and inflammation. This book reviews the FcR for the different immunoglobulin isotypes, focusing on the structural bases of their biological functions.
Publisher: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Weight: 640 g
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