This book offers a unique combination of succinctly expressed basic concepts of cell growth and cell death, particularly by apoptosis, and detailed instructions and protocols on how accurately to measure these processes. Experts in each line of these investigations describe a range of techniques which will enable weve an inexperienced reader to determine with precision such cellular events as the cell cycle traverse, chromosomal abnormalities detected at cell division, DNA damage that causes these abberrations, and cell death, or cell senescence. Establishment of the cell lines for studies is illustrated with reference to leukaemic cells, and optimization of cell proliferation by growth factors is also described. Together, these contributions form a useful laboratory manual for studies of growth abnormalities in human cell.
Publisher: Oxford University Press
Number of pages: 296
Weight: 510 g
Dimensions: 234 x 156 x 17 mm
Is there a market for this book? The answer is a questionable yes ... a good buy. * T. Cotter, Br. J. Biomed Sci 1996 *
the book is very readable, and, from the point of view of the quality/price ratio, is a good value for money ... This manual will be undoubtedly very useful to many scientists that sooner or later will finish to work in apoptosis, even if their initial aims were to work in cell proliferation. * Javier Naval and Alberto Anel, Universidad de Zaragoza, FEBS Letters 408 (1997) *