Cell Culture Engineering - Advances in Biochemical Engineering/Biotechnology 101 (Hardback)
  • Cell Culture Engineering - Advances in Biochemical Engineering/Biotechnology 101 (Hardback)
zoom

Cell Culture Engineering - Advances in Biochemical Engineering/Biotechnology 101 (Hardback)

(editor)
£249.99
Hardback 168 Pages / Published: 23/08/2006
  • We can order this

Usually dispatched within 3 weeks

  • This item has been added to your basket
Since the introduction of recombinant human growth hormone and insulin a quarter century ago, protein therapeutics has greatly broadened the ho- zon of health care. Many patients suffering with life-threatening diseases or chronic dysfunctions, which were medically untreatable not long ago, can attest to the wonder these drugs have achieved. Although the ?rst generation of p- tein therapeutics was produced in recombinant Escherichia coli, most recent products use mammalian cells as production hosts. Not long after the ?rst p- duction of recombinant proteins in E. coli, it was realized that the complex tasks of most post-translational modi?cations on proteins could only be ef?ciently carried out in mammalian cells. In the 1990s, we witnessed a rapid expansion of mammalian-cell-derived protein therapeutics, chie?y antibodies. In fact, it has been nearly a decade since the market value of mammalian-cell-derived protein therapeutics surpassed that of those produced from E. coli. A common characteristic of recent antibody products is the relatively large dose required for effective therapy, demanding larger quantities for the treatment of a given disease. This, coupled with the broadening repertoire of protein drugs, has rapidly expanded the quantity needed for clinical applications. The increasing demand for protein therapeutics has not been met exclusively by construction of new manufacturing plants and increasing total volume capacity. More - portantly the productivity of cell culture processes has been driven upward by an order of magnitude in the past decade.

Publisher: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
ISBN: 9783540340065
Number of pages: 168
Weight: 970 g
Dimensions: 235 x 155 x 12 mm
Edition: 2006 ed.

You may also be interested in...

Genes, Cells and Brains
Added to basket
Biomaterials
Added to basket
£69.99
Paperback
Starved for Science
Added to basket
Bionanotechnology II
Added to basket
Gene Cloning
Added to basket
£47.99
Paperback
From Genes to Genomes
Added to basket
Genetics
Added to basket
£9.99
Paperback
Mind Wars
Added to basket
£14.99
Paperback
Bacterial Disease Mechanisms
Added to basket
From Alchemy To Ipo
Added to basket

Reviews

Please sign in to write a review

Your review has been submitted successfully.