Visit our Christmas Gift Finder
Blood Cell Biochemistry: Hematopoiesis and Gene Therapy - Blood Cell Biochemistry 8 (Hardback)
  • Blood Cell Biochemistry: Hematopoiesis and Gene Therapy - Blood Cell Biochemistry 8 (Hardback)
zoom

Blood Cell Biochemistry: Hematopoiesis and Gene Therapy - Blood Cell Biochemistry 8 (Hardback)

(editor), (editor)
£179.99
Hardback 380 Pages / Published: 31/03/1999
  • We can order this

Usually dispatched within 3 weeks

  • This item has been added to your basket
Since the first concepts of gene therapy were formulated, the hemopoietic system has been considered the most natural first target tissue for genetic manipulation. The reasons for this include the fact that a very large number of inherited disorders (including some of the most common disorders, such as the hemoglobinopathies) are disorders of the hemopoietic system, and the large amount of experience in hematopoietic transplantation biology. The consequence of this resulted in the first clinical trial of gene therapy in 1989, where two children suffering from severe combined immune deficiency (ADA-SCID) were transplanted with T-cells express- ing adenosine deaminase (the defective enzyme in patients with this disorder). The partial success of this treatment was perhaps responsible for undue optimism among those proposing other gene therapy treatments within the hematopoietic system, and it has since become clear that there are a number of technical and biological difficulties to overcome before hematopoietic gene therapy becomes a mainstream therapeutic strategy. The chapters in this book evaluate the need for gene therapy in the hematopoietic system, discuss how efficient gene transfer and expression can be achieved in the target cells, highlight areas of difficulty to be addressed, and examine a number of potential applications of the gene therapy approach. The book begins with a chapter by Testa and colleagues, discussing the various sources of hematopoietic cells for both transplantation and gene therapy.

Publisher: Springer Science+Business Media
ISBN: 9780306459627
Number of pages: 380
Weight: 2150 g
Dimensions: 254 x 178 x 22 mm
Edition: 1999 ed.

You may also be interested in...

Contented Dementia
Added to basket
£14.99
Paperback
Healthy Eating for Diabetes
Added to basket
Irritable Bowel Solutions
Added to basket
A Dictionary of Psychology
Added to basket
Concise Medical Dictionary
Added to basket
The Autistic Brain
Added to basket
Dementia: The One-Stop Guide
Added to basket
Concise Colour Medical Dictionary
Added to basket
£14.99
Part-work (fascículo)
Reverse Your Diabetes
Added to basket
Radical Remission
Added to basket
The Complete Guide to Asperger's Syndrome
Added to basket
The Emperor of All Maladies
Added to basket
The Female Brain
Added to basket
The Brain: A Very Short Introduction
Added to basket

Please sign in to write a review

Your review has been submitted successfully.