This book is a comprehensive compendium of current knowledge on inherited and autoimmune blistering diseases that relates advances in our understanding of the pathogenetic mechanisms to management of the individual diseases. The aim is to provide a detailed reference for dermatologists who care for patients with these conditions and a useful "one-stop information shop" for specialists outside of dermatology. The book opens by describing the structure and biology of the epidermis and basement membrane zone and discussing the genes and proteins that are targets for mutations and autoantibodies. The role of the various diagnostic tests is explained, and clinical manifestations of the specific diseases are presented with the aid of many high-quality illustrations. The forms of treatment appropriate in specific conditions are then described in depth, with coverage of dressings, drugs, surgical procedures, gene therapy, and other novel approaches. Helpful algorithms are included both for testing and monitoring and for treatment.
Publisher: Springer-Verlag Berlin and Heidelberg GmbH & Co. KG
Number of pages: 752
Weight: 1960 g
Dimensions: 254 x 178 mm
Edition: Softcover reprint of the original 1st ed. 201
"This is a true textbook, presenting a thorough and well-organized discussion of a complex and often difficult area of dermatology. It presents the most complete discussion of blistering diseases I have ever encountered. And it manages to organize this wealth of information clearly, so the book can be used for quick reference as well as for complete reading. This is a valuable reference for any practicing dermatologist, training resident, or researcher in this field." (Kathleen E. Kramer, Doody's Book Reviews, September, 2016)