Applied Surrogate Endpoint Evaluation Methods with SAS and R - Chapman & Hall/CRC Biostatistics Series (Hardback)Ariel Alonso (author), Theophile Bigirumurame (author), Tomasz Burzykowski (author), Marc Buyse (author), Geert Molenberghs (author), Leacky Muchene (author), Nolen Joy Perualila (author), Ziv Shkedy (author), Wim Van der Elst (author)
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An important factor that affects the duration, complexity and cost of a clinical trial is the endpoint used to study the treatment's efficacy. When a true endpoint is difficult to use because of such factors as long follow-up times or prohibitive cost, it is sometimes possible to use a surrogate endpoint that can be measured in a more convenient or cost-effective way. This book focuses on the use of surrogate endpoint evaluation methods in practice, using SAS and R.
Publisher: Apple Academic Press Inc.
Number of pages: 374
Weight: 703 g
Dimensions: 235 x 156 mm
"This is a timely text. The number of published studies using surrogate endpoints has increased dramatically since the early work of the 1980s; however, there is a dearth of available texts or software on this topic. Anyone with an interest in surrogate endpoint evaluation would benefit from this text."
~Statistics in Medicine
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